At a Glance
The Red Devils' poor run of form continued at Elland Road, but manager Ruben Amorim had Matheus Cunha to thank for the team avoiding even more damage against Leeds.
The Everton loanee headed a first-period attempt against the woodwork for the confident home team before Brenden Aaronson applied a cool finish with a low, 62nd-minute shot.
With the goal, the United boss was in the firing line after his side had been held by struggling Wolves at Old Trafford earlier in the week.
Nevertheless, against opponents who had two days less to prepare, Cunha restored parity three minutes later when he ran on to a through ball from substitute Joshua Zirkzee and guided a finish underneath rushing home goalkeeper Lucas Perri.
It was only the Brazilian's fourth Premier League goal since his high-profile summer move and came at a time when Amorim is without several key attacking players due to a mix of fitness issues and international duty.
Not that you would expect Leeds to sympathise with that given their own lack of preparation time.
Noah Okafor forced a full length save out of Manchester United goalkeeper Senne Lammens with a spectacular overhead kick, and United heads were in hands when Benjamin Sesko, who is struggling to make an impression, turned his teammate's cut-back wide from close range.
The goalscorer, who had a goal disallowed for offside much earlier in the contest, also blasted against a post in the dying moments.
The draw prolongs the home side's unbeaten run to seven games, their longest such streak since over two decades ago, and takes them eight points clear of the drop zone.
For the visitors though, it was yet another chance to move into fourth spot, albeit only for a matter of hours, wasted.
With the AFCON reaching its latter stages, the United coach could be understood for hoping the involved countries make a pretty quick exit.
Current injuries to captain Bruno Fernandes and England international Mason Mount only exacerbated the impact the unavailability of other forwards is having on Amorim's squad.
It's not that the absent players are the solution to all of United's problems. After all, they were part of the side that suffered disappointing results earlier in the season.
But without them, the boss has few attacking options.
He evidently does not trust youngster Shea Lacey or the seasoned Joshua Zirkzee, even though the Dutch forward provided the through ball for the equaliser almost immediately after his introduction as a replacement.
That leaves Cunha, who has now scored a small tally in five games, and others operating out of their natural positions, alongside Benjamin Sesko.
On this evidence, the big-money frontman looks no better than previous struggling signings, lacking in confidence and assurance in front of goal.
Sesko's failure to turn home the cross means it is now nine games without a goal for the young striker.
After memorable victories in their last few home games, the arrival of their biggest rivals to Elland Road was a bit drab affair.
True, there were moments of expected atmosphere, but the intimidating edge was not as evident as in previous fixtures.
Leeds' fans were more concerned about their side's struggle to get worthwhile possession in dangerous areas for any prolonged period.
The Calvert-Lewin header that struck the post was an isolated moment of threat in a tight first half.
It still felt as though Leeds were finding it tough when a defensive error opened the door for Aaronson.
For a short moment, The home delirious fans thought they were about to secure a rare win against their old foes.
However, there is a wider context for the manager and the club to deal with.
When they suffered a difficult run of form earlier in the campaign, many speculated about the manager's position.
In contrast, he is now overseeing clear improvement.
The task is not done yet but gradually, Leeds are getting nearer to achieving their top-flight status.
The Yorkshire club have a Premier League trip to Newcastle in midweek, followed by the start of their domestic cup campaign next weekend. The Red Devils face a Premier League trip to Turf Moor before also beginning their cup journey with a Old Trafford tie.